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Neurotransmitter Transporter Uptake Assay Kit

Neurotransmitter Transporter Uptake Assay Kit

  • $197.00



Please note: All purchases should be limited to United States.

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Until recently, radioactively labeled compounds were used to measure serotonin, norepinephrine and dopamine transporter uptake. With the introduction of the Neurotransmitter Transporter Uptake Assay Kit, researchers now have a tool to screen for live-cell kinetic uptake for these three key neurotransmitters.

Key Benefits

  • Homogeneous, live-cell fluorescent assay replaces radioactive assays, reducing disposal costs and eliminating safety risks associated with radiolabeled assays
  • One-step, homogeneous assay format is amenable to automation and high-throughput screening
  • Two assay setup options offer greater flexibility: endpoint mode for high-throughput applications, or real-time kinetic mode for mechanistic studies


Patented Technology
This assay utilizes a Molecular Devices masking dye to extinguish extracellular fluorescence. This masking dye technology has been exclusively licensed from Bayer AG (U.S. Patent Nos. 6,420,183, 7,063,952, 7,138,280 and European Patent No. 0,906,572). The assay also includes a novel proprietary fluorescent indicator dye that mimics the neurotransmitters serotonin, norepinephrine, and dopamine, and is actively transported into the cells via the neurotransmitter transporters.

       

       

      Available Configurations:

       Configuration Description Part Number

      Evaluation Kit - 2 Plates

      • (2) vials of lyophilized fluorescent dye/masking dye mix
      • Each vial is sufficient for one (1) 96-well or 384-well plate
      •  Each kit is sufficient for 2 plates total
      (R6138)
      Explorer Kit - 5 Plates
      • (5) vials of lyophilized fluorescent dye/masking dye mix
      •  Each vial is sufficient for one (1) 96-well or 384-well plate
      • Each kit is sufficient for 5 plates total
      (R8173)
      Bulk Kit - 50 Plates
      • (5) vials of lyophilized fluorescent dye/masking dye mix
      • Each vial is sufficient for ten (10) 96-well or 384-well plates
      • Each kit is sufficient for 50 plates total
      (R8174)

       

       


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