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EarlyTox Glutathione Assay Kit

*Terms and Conditions
50% off the list price. Promotion is available in the United States only when buying directly from Molecular Devices. Purchase order must reference promotion code 50AssayKits17. The offer is to purchase any of the following: EarlyTox Cell Viability Assay Kits, SpectraMax Glo Steady-Luc Reporter Assay Kit, or SpectraMax Quant dsDNA Assay Kit. Valid August 3, 2017 through August 31, 2017. The offer does not include any other options or accessories. This promotion cannot be combined with any other promotions or discounts. No substitutions or swap outs. The discount is not convertible to cash. All prices exclude delivery charges and local taxes, which are the responsibility of the customer. Purchase orders must be received by August 31, 2017. Promotion is not valid for standing orders. The purchase is subject to Molecular Devices standard terms and conditions of sale. All products are for research use only. Void where prohibited. Product Purchase Terms – US.

EarlyTox Glutathione Assay Kit

  • $160.00

50% OFF* Use Code 50AssayKits17 at Check Out





This kit enables the detection of an early apoptosis event based on the measurement of the glutathione content in live mammalian cells using a fluorescence microplate reader. Diminished cellular glutathione (GSH), which is an important anti-oxidant in mammalian cells, occurs at the early stages of mitochondria-associated apoptosis because of GSH efflux. This kit uses monochlorobimane (MCB), a cell permeant dye that has a high affinity for GSH, to detect the cellular GSH level in an apoptotic event. The unreacted dye is almost non-fluorescent. After reaction of the dye with GSH, catalyzed by endogenous glutathione-S-transferase (GST) enzymes, the dye fluoresces blue, with excitation at 394 nm and emission at 490 nm. The intensity of the fluorescence signal generated from the assay reflects the amount of GSH that is present in the cells.

     

     

    Available Configurations:

     Configuration Description Part Number

    Explorer Kit

    • (1) vial of MCB (10 mM, 100 µL)

      Each kit contains enough material for two (2) 96-well or 384-well microplates.
    (R8344)
    Bulk Kit
    • (1) vial of MCB (10 mM, 500 µL)

      Each kit contains enough material for ten (10) 96-well or 384-well microplates.
    (R8345)

     

     


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